http://repository.matanauniversity.ac.id:8080/xmlui/123456789/99 2026-09-02T15:58:49Z http://repository.matanauniversity.ac.id:8080/xmlui/123456789/1689 Evaluation of noise values and homogenity of CT scan image results on head phantom after daily calibration Samaliwu, Evelin Trivena; Illya, Gregoria Evaluation of CT scan image quality is a crucial aspect in ensuring accurate medical diagnosis. This research aims to evaluate noise values and image homogeneity of CT scans on a head phantom after daily calibration. Evaluation of these two parameters is critical because high noise can interfere with image contrast and lead to clinical misinterpretation, while low homogeneity may indicate artifacts or system inconsistencies that potentially reduce diagnostic reliability. Measurements were performed using Region of Interest (ROI) at five points (one in the center and four at the edges at 12, 3, 6, and 9 o'clock positions) across six image slices, for both head and body modes. The CT scan system used was Siemens SOMATOM go.Top, with primary scanning parameters for each mode: 120 kV voltage, 265 mA current (head) and 220 mA (body), as well as Hr40f and Br40f kernels. Research results show that the CT number homogeneity values in head mode ranged from -1.96 to 0.81 HU, and in body mode from -1.78 to 1.28 HU; all were within the tolerance limit of 0 ± 4 HU. Noise values for head mode ranged from 3.49 – 3.67 HU and body mode from 4.98 – 5.37 HU, also within standard tolerance limits. These findings indicate that the CT scan system functions properly and meets diagnostic imaging quality standards. Additionally, these results support the importance of implementing periodic quality control as part of improving radiological service quality and strengthening patient safety standards in medical facilities 2025-07-31T00:00:00Z http://repository.matanauniversity.ac.id:8080/xmlui/123456789/1688 Composition-Dependent Structural and Dynamical Properties of Mixed DPPC/DLPC Bilayers: An Atomistic Molecular Dynamics Study Illya, Gregoria; Sutanto, Hadi Moderate chain-length mismatch in saturated lipid mixtures provides a useful model for understanding how structural perturbations influence membrane behavior. Here, all-atom molecular dynamics simulations were used to investigate DPPC/DLPC bilayers across compositions at 50 °C, focusing on the coupled evolution of structure, dynamics, and hydration. Increasing DLPC content leads to a systematic increase in area per lipid and a reduction in bilayer thickness, indicating weakened packing within the hydrophobic core. These structural changes are accompanied by enhanced interleaflet coupling and decreased acyl-chain ordering. The lateral diffusion behavior is composition-dependent: DLPC mobility increases steadily with concentration, whereas DPPC exhibits a non-monotonic trend, reflecting competing effects of increased free volume and heterogeneous packing. Mean squared displacement analysis in log–log representation reveals persistent subdiffusive dynamics for both lipid species, with diffusion exponents α ≈ 0.30–0.35 across all compositions. This indicates that lipid motion remains governed by transient confinement and spatial heterogeneity, even as overall mobility increases. In parallel, water density profiles show enhanced penetration of water into the bilayer interior with increasing DLPC fraction, driven by packing defects and increased free volume rather than pore formation. These results demonstrate that moderate chain-length mismatch induces a coupled structural and dynamical response that governs membrane transport properties 2026-08-31T00:00:00Z http://repository.matanauniversity.ac.id:8080/xmlui/123456789/1656 Implementation of Community-Based Tourism As Sustainable Tourism Development Strategy on Pari Island, Seribu Islands Simamora, Vera Inne Juni; Nando, Felix; Lawrence, Jennifer The achievement of long-term tourism sustainability requires active participation from local communities, particularly through Community-Based Tourism (CBT) implementation, which can generate benefits across economic, socio-cultural, and environmental dimensions. Although Pari Island has significant marine tourism potential, the implementation still faces various challenges, particularly regarding institutional frameworks, community participation, and environmental management. This research analyzes the implementation of Community-Based Tourism (CBT) on Pari Island across economic, environmental, and socio-cultural dimensions, and identifies forms of government support for CBT. A qualitative approach utilizing descriptive methods was adopted. Informants comprised tourism business actors, administrators of Tourism Awareness Groups (Pokdarwis), community leaders, and local government representatives, all selected through purposive sampling. Data were obtained from several sources, including in-depth interviews, field observations, and relevant documentation. The data were then systematically interpreted using a thematic analysis approach. The results demonstrate that the economic dimension is the most developed aspect of community-based tourism (CBT), as shown by community participation in diverse tourism enterprises that increase income and create employment opportunities. In contrast, the socio cultural and environmental dimensions remain underdeveloped due to limited collective community participation, weak local institutions, insufficient stakeholder collaboration, and low community engagement in environmental management. Government support has been provided through facilities, training, and sanitation management, but lacks sustained institutional backing. These results highlight the necessity of strengthening community institutions, fostering multi-stakeholder collaboration, and advancing community-based environmental management to enhance CBT implementation and promote sustainable tourism development on Pari Island. 2026-01-01T00:00:00Z http://repository.matanauniversity.ac.id:8080/xmlui/123456789/1655 Unlocking Drug Delivery Potential: The Crucial Role of Liposome Mechanical Properties Illya, Gregoria The mechanical properties of liposomes play a critical role in determining their stability, drug release behavior, biodistribution, and interaction with biological barriers. These properties are primarily governed by lipid composition, including the degree of acyl chain saturation, tail length, and headgroup charge. Cholesterol incorporation is a widely used strategy to increase membrane rigidity by condensing the bilayer and reducing permeability. Temperature also modulates mechanical behavior, with liposomes transitioning from a rigid gel phase below the lipid phase transition temperature to a more fluid and permeable liquid-crystalline phase above it. Structural features such as liposome size and lamellarity further influence mechanical performance, larger liposomes tend to be more flexible, whereas multilamellar vesicles exhibit greater stiffness. Precisely controlling liposome stiffness through careful manipulation of their mechanical properties is a fundamental design principle for creating more effective nanocarriers in cancer therapy. Achieving moderate liposome stiffness is particularly advantageous, as it can result in extended circulation within the bloodstream and enhanced accumulation within tumors by exploiting the enhanced permeability and retention effect. 2026-03-21T00:00:00Z